Climate change is a global environmental threat to all economic activities, especially the livestock activity. The South of Tunisia, where animal husbandry is a fundamental element of the domestic economy, is more influenced by these negatives effects due to the arid climate. The objective of this study is to identify strategies and levers mitigation and adaptation to climate change developed by breeders on based on available factors. For this purpose, a survey conducted among 73 breeders on the rangelands of El Ouara, in the South of Tunisia. Results emerges that breeders use various adaptation strategies principally, supplementation, integration agriculture-livestock and conduct’s mode through different types such as association. The result of the model reveal that age of breeder, herd size, agricultural area, member of an association, subsidies and well ownerships are the most factors which significantly influence the adaptation choices of breeders to cope to climate change. The results proved too that adaptation to climate change was inhibited by many factors such as luck of workforce labor, lack of water and financial resources as well the degradation of the rangelands.